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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of atopic cataract
ncRNA name PAI-1 siRNA
ncRNA Category siRNA
Disease name atopic cataract
Species Homo sapiens
Tissues/Cell_line human lens epithelial cell line SRA01/04
Methods qPCR, immunohistochemistry, electron microscopy, siRNA transfection, Western blot
Expression pattern associated
Functional description PAI-1 gene knockdown resulted in reduced α-SMA expression in the LECs.
PubMed ID 22410565
Year 2012
Title Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts.
Drug-related ncRNA NO

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